In silico modeling of protein-protein interactions of human Krüppel-like zinc finger 10 gene product with transcriptional inhibitors SnoN and Ski: analysis of gene polymorphisms’ effects as the potential reason for cardiac hypertrophic  myopathies

dc.contributor.author	Kravchuk, Sophia
dc.date.accessioned	2024-02-14T08:56:38Z
dc.date.available	2024-02-14T08:56:38Z
dc.date.issued	2022
dc.identifier.citation	Kravchuk, Sophia. In silico modeling of protein-protein interactions of human Krüppel-like zinc finger 10 gene product with transcriptional inhibitors SnoN and Ski: analysis of gene polymorphisms’ effects as the potential reason for cardiac hypertrophic myopathies / Kravchuk, Sophia; Supervisor: Olexandr Korchynsky; Ukrainian Catholic University, Department of Computer Sciences. – Lviv: 2022. – 48 p.	uk
dc.identifier.uri	https://er.ucu.edu.ua/handle/1/4400
dc.language.iso	en	uk
dc.title	In silico modeling of protein-protein interactions of human Krüppel-like zinc finger 10 gene product with transcriptional inhibitors SnoN and Ski: analysis of gene polymorphisms’ effects as the potential reason for cardiac hypertrophic myopathies	uk
dc.type	Preprint	uk
dc.status	Публікується вперше	uk
dc.description.abstracten	In this thesis, it will be explored the structure of the human Krüppel-like zinc finger 10 gene and protein, its single nucleotide polymorphisms, and how they affect the protein. It will be shown the interactions between Krüppel-like zinc finger 10 with Ski and with SnoN proteins. The analysis of single nucleotide polymorphisms’ potential influence on the repressive function of the protein complex and its connection to hypertrophic cardiomyopathy will be discussed.	uk